Right now a pretty stupidly constructed spambot is hammering away at my comment function and clogging up my moderation queue - nothing gets through from it because it's so stupid that it posts everything in plain text, loads of links and typical spam words. So it gets caught by the most basic filters. Nonetheless, something like this can of course have fallout - namely comments from others that end up in moderation (e.g. because the number of links is too high) could be overlooked by me in the mess of hundreds of spam comments and accidentally deleted along with it. If that happens, it's not personal. I just don't feel like scrutinizing carefully when dealing with several hundred spam comments to make sure I'm really only deleting spam...
Update: After taking a closer look at it, I've put it in /dev/null for now - the moderation queue is no longer burdened by it and legitimate moderated comments won't accidentally get deleted. What struck me during the closer examination: a large number of very widely scattered IP addresses are being used. Sounds very much like a botnet, especially since the IP addresses, based on spot checks, appear to all be dynamic dialup addresses. So our friends with remotely controlled Windows machines are once again the horse that spam rides on here. Great. Thanks, Microsoft...